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Emphysema is a chronic lung disease that reduces
the lungs' ability to expand and contract. |
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When the air sacs in the lungs cannot expand and contract
normally, less oxygen passes through the lungs to the body. |
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Cigarette smoking is the major cause of emphysema. |
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Diagnosis of emphysema is based on a review of symptoms,
lung function tests, breathing patterns and, sometimes, x-rays
or CT scans. |
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A substance called alpha-1 antitrypsin (AAT) is thought to
protect against some of the damage caused by cigarette smoke
or other irritants. People with alpha-1 antitrypsin deficiency
(AAT deficiency) are at a higher risk for severe disease. |
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A blood test can establish the diagnosis of AAT deficiency. |
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There is currently no cure for emphysema, but the symptoms
can be lessened with medication, supplemental oxygen, and proper
nutrition |
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For people with emphysema due to AAT deficiency, weekly infusions
of alpha 1-proteinase inhibitor may slow lung tissue destruction.
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